La Ricerca in SFU

ABSTRACT

Background: Patients with advanced Chronic Obstructive Pulmonary Disease (COPD) experience effort dyspnea despite maximal drug therapy. Respiratory BF (R-BF) uses sensors for monitoring of electrophysiological parameters and consisted in the patient’s progressive education in slow and deep breathing (1). We aim to assess if R-BF training in addition to pulmonary rehabilitation (PR) in patients with optimal pharmacological therapy may determine a benefit on of effort dyspnea.

Methods: 17 stable COPD patients (all E group) with modified Medical Research Council(mMRC)>3 despite maximal pharmacological therapy were consecutively enrolled for 6 months and randomly divided into two groups: group 1, intervention group(PR+BF); group 2, control group(only PR). The study outcomes were: mMRC, BORG dyspnea, BARTHEL dyspnea, SPPB, 6-minute walk test distance (6MWD), St. George Respiratory Questionnaire (SGRQ), EuroQOL-5 Dimension Questionnaire (EQ-5D™), Montreal Cognitive Assessment (MoCA Test), The Hospital Anxiety and Depression Scale (HADS A and D)

Results: after rehabilitation, mMRC, BORG D, BARTHEL dyspnea and quality of life questionnarire increased in both groups. In addition, only group 1 showed improvement in 6MWD(p=0.041) and in cognitive domains(p=0.006), specifically in:Executive Functions(p=0.015), Memory(p=0.019), Language(p=0.045), Orientation(p=0.046)

Conclusions: R-BF does not provide additional benefit on dyspnea, but in combination with PR may promote additional benefits not only on motor but also cognitive outcomes in COPD patients with effort dyspnea despite optimal therapy

https://doi.org/10.1183/13993003.congress-2024.PA3186

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The assessment of personality pathology based on dimensional models may improve self–other agreement, but previous research mainly adopted a categorical approach and overlooked the role of the person of the therapist. Our study examined patient–clinician agreement in a mixed sample of Italian outpatients using the Personality Inventory for DSM-5 (PID-5) and the PID-5-Informant Form (PID-5-IRF). Moreover, the role of clinician personality traits on agreement was preliminary explored. Sixty-eight outpatients (51.4% male, M = 30.30, SD = 12.05 years) and their treating clinicians (N = 22; 77.3% female, M = 43.77 ± 8.45 years) entered the study. Patients completed the PID-5, whereas clinicians filled-in the PID-5-Brief Form (PID-5-BF) and the PID-5-IRF for each patient they involved. A multilevel Bayesian analysis showed that rank–order agreement was large for domains (mean r = .60) and moderate for facets (mean r = .44). As regards mean-level agreement, patient ratings on cognitive/perceptual dysregulation, distractibility, eccentricity, and emotional lability were higher than clinician ratings, whereas patients’ scores on depressivity were lower than clinicians’ ones. Scores on the PID-5-BF detachment positively predicted agreement on anhedonia, anxiousness, depressivity, distractibility, separation insecurity, and suspiciousness, while scores on the PID-5-BF negative affectivity, antagonism, and disinhibition negatively predicted agreement on few specific facets. Current findings suggest that clinician personality traits may contribute to agreement on maladaptive personality traits, but areas of discrepancies remain in case of low observable internal ones. Since patient–clinician agreement is crucially involved in therapeutic alliance, further research on this issue is highly encouraged. (PsycInfo Database Record (c) 2024 APA, all rights reserved)

https://doi.org/10.1037/per0000639

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Background: Diagnosis of child and adolescent psychopathologies involves a multifaceted approach, integrating clinical observations, behavioral assessments, medical history, cognitive testing, and familial context information. Digital technologies, especially internet-based platforms for administering caregiver-rated questionnaires, are increasingly used in this field, particularly during the screening phase. The ascent of digital platforms for data collection has propelled advanced psychopathology classification methods such as supervised machine learning (ML) into the forefront of both research and clinical environments. This shift, recently called psycho-informatics, has been facilitated by gradually incorporating computational devices into clinical workflows. However, an actual integration between telemedicine and the ML approach has yet to be fulfilled.

Objective: Under these premises, exploring the potential of ML applications for analyzing digitally collected data may have significant implications for supporting the clinical practice of diagnosing early psychopathology. The purpose of this study was, therefore, to exploit ML models for the classification of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) using internet-based parent-reported socio-anamnestic data, aiming at obtaining accurate predictive models for new help-seeking families.

Methods: In this retrospective, single-center observational study, socio-anamnestic data were collected from 1688 children and adolescents referred for suspected neurodevelopmental conditions. The data included sociodemographic, clinical, environmental, and developmental factors, collected remotely through the first Italian internet-based screening tool for neurodevelopmental disorders, the Medea Information and Clinical Assessment On-Line (MedicalBIT). Random forest (RF), decision tree, and logistic regression models were developed and evaluated using classification accuracy, sensitivity, specificity, and importance of independent variables.

Results: The RF model demonstrated robust accuracy, achieving 84% (95% CI 82-85; P<.001) for ADHD and 86% (95% CI 84-87; P<.001) for ASD classifications. Sensitivities were also high, with 93% for ADHD and 95% for ASD. In contrast, the DT and LR models exhibited lower accuracy (DT 74%, 95% CI 71-77; P<.001 for ADHD; DT 79%, 95% CI 77-82; P<.001 for ASD; LR 61%, 95% CI 57-64; P<.001 for ADHD; LR 63%, 95% CI 60-67; P<.001 for ASD) and sensitivities (DT: 82% for ADHD and 88% for ASD; LR: 62% for ADHD and 68% for ASD). The independent variables considered for classification differed in importance between the 2 models, reflecting the distinct characteristics of the 3 ML approaches.

Conclusions: This study highlights the potential of ML models, particularly RF, in enhancing the diagnostic process of child and adolescent psychopathology. Altogether, the current findings underscore the significance of leveraging digital platforms and computational techniques in the diagnostic process. While interpretability remains crucial, the developed approach might provide valuable screening tools for clinicians, highlighting the significance of embedding computational techniques in the diagnostic process.

https://doi.org/10.2196/54577

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Problematic mobile phone use (PMPU) has become a worldwide phenomenon with negative impacts on adolescents’ daily lives. While self-control has been shown to be related to PMPU, little is known about the underlying mechanisms of this association. Based on the Interaction of Person-Affect-Cognition-Execution model and the strength model of self-control, the current study aims to examine the association between self-control and PMPU, to identify the indirect role of craving, and to determine whether and how the two components of desire thinking exert differential moderating effects. A sample of 1424 adolescents was recruited to complete the scales of self-control, craving, desire thinking, and PMPU. The results suggested that self-control was indirectly associated with PMPU through craving. Furthermore, this indirect association was moderated by verbal perseveration, rather than imaginal prefiguration. Specifically, the indirect association was stronger for adolescents with higher verbal perseveration. The findings deepen our understanding of how self-control is related to PMPU and distinguish the effects of two components of desire thinking among adolescents.

https://doi.org/10.1016/j.jpsychires.2024.09.004

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Using the Elaborated Intrusion Theory of Desire and the Self-Regulatory Executive Function model of psychopathology as bases, this study explored whether metacognitive beliefs and desire thinking (DT) are associated with higher levels of Compulsive Sexual Behavior (CSB). A total of 1185 participants from the general population were included in the study (mean ± SD age = 25.32 years ± 5.58; age range = 18–19 years; females = 76.7 %). Metacognitive beliefs, DT, CSB, anxiety and depressive symptoms were assessed. Correlation analyses and path analyses were run. Results of the path analysis showed that positive metacognitive beliefs about DT were associated with DT-Imaginal Prefiguration (DT-IP), which in turn was positively associated with DT-Verbal Perseveration (DT-VP). The latter was strongly and positively associated with negative metacognitive beliefs about DT, which in turn was linked to CSB. Moreover, DT-VP was also found to be directly linked to the outcome variable and positive metacognitive beliefs about DT were also directly linked to DT-VP and negative metacognitive beliefs about DT. The total Coefficient of Determination (0.45) indicated a good fit to the observed data. Metacognitive beliefs and DT may be potential maintenance factors in CSB. Metacognitive beliefs and DT could also be considered as potential therapeutic targets in clinical interventions aimed at reducing the severity of CSB.

https://doi.org/10.1016/j.addbeh.2024.108214

ABSTRACT

Introduction
Using the Self-Regulatory Executive Function model as a basis, this study explored whether, in patients with eating disorders (EDs), metacognitions and repetitive negative thinking are associated with higher levels of perfectionisms.

Methods
One hundred twenty-three outpatients with EDs were recruited. Perfectionism, metacognitive beliefs, worry, rumination, anger rumination, affective and eating symptoms were assessed. Correlation and hierarchal regression analyses were run.

Results
Higher endorsement of positive beliefs about worry was associated with higher levels of ‘personal standards perfectionism’. Higher endorsement of positive beliefs about worry, need to control thoughts, worry and rumination was associated with higher levels of ‘concern over mistakes perfectionism’.

Conclusions
Among patients with EDs, perfectionism appears to be associated with the endorsement of dysfunctional metacognitive beliefs, worry and rumination. Dysfunctional metacognitive beliefs and repetitive negative thinking could be suitable therapeutic targets to reduce the levels of perfectionism among patients with EDs.

https://doi.org/10.1002/cpp.2954

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Although a probable association between metacognitive beliefs (also termed ‘metacognitions’) and emotion dysregulation has been suggested in the literature, the evidence is still sparse and inconclusive. The current study aims to present a comprehensive evaluation of the literature examining the association between metacognitive beliefs and emotion dysregulation. In accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria, a search was conducted on PubMed and Ebsco. A manual search of reference lists was also run. Search terms were ‘metacognitions/metacognitive beliefs/positive metacognitive beliefs/negative metacognitive beliefs/cognitive self-consciousness/beliefs about the need to control thoughts/cognitive confidence/negative beliefs about thoughts concerning uncontrollability and danger/AND difficulties emotion regulation/emotion dysregulation’. A total of 19 studies met the inclusion criteria. In both non-clinical and clinical populations, a higher endorsement of dysfunctional metacognitive beliefs was found to be associated with emotion dysregulation and vice versa. A higher endorsement of metacognitive beliefs may be associated, either directly or via maladaptive forms of mental control (e.g., worry, rumination and suppression) to emotion dysregulation. Metacognitive beliefs could be the potential therapeutic target in clinical interventions aimed at reducing emotion regulation difficulties.

https://doi.org/10.1002/cpp.2961

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This study aimed to evaluate the possible mediating role of psychological flexibility in the association between fear of COVID-19, affective symptoms and well-being. 403 subjects were recruited; fear of COVID-19, psychological flexibility, affective symptoms and well-being were assessed via self-report measures. Correlation and mediation analyses were run. Psychological flexibility was found to play a mediating role in the association between fear of COVID-19 and more severe affective symptoms (adjusted R-squared = 52%, p < 0.001), and between fear of COVID-19 and poor well-being (adjusted R-squared = 41%, p < 0.001). Psychological flexibility may mitigate the negative impacts of fear of COVID-19 on affective symptoms and well-being Psychological flexibility could be the potential therapeutic target in clinical interventions aimed at reducing the adverse effects of fear of COVID-19 on mental health.

https://doi.org/10.1007/s10942-024-00556-z

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https://doi.org/10.1002/cpp.3020

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https://doi.org/10.1016/j.jad.2024.07.144

https://doi.org/10.1002/cpp.70014

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Obesity is a major public health challenge and results from the complex interaction of many etiopathogenetic factors. However, food-related hedonic stimuli and poor inhibitory control often appear to be specific maintenance factors, and conventional treatments are sometimes ineffective. Transcranial magnetic stimulation is emerging as a promising treatment option. Targeting specific brain regions, such as the dorsolateral prefrontal cortex, was found to be effective in modulating acute food craving and improving cognitive control. This review traces the evolution and development of transcranial magnetic stimulation and presents the results of recent randomized clinical trials conducted in obese subjects. These suggest that repetitive transcranial magnetic stimulation and deep transcranial magnetic stimulation may be effective in reducing body weight, BMI and food cravings. The neural circuits involved and the underlying mechanisms of action of this neurostimulation technique are also reviewed. Finally, outstanding questions and future research directions are identified to further understand and develop this promising therapy.

https://doi.org/10.2174/011874205X309047240503104533

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This study explores the interplay between executive functions and body weight, examining both the influence of biological factors, specifically sex, and methodological issues, such as the choice between Body Mass Index (BMI) and waist circumference (WC) as the primary anthropometric measure. A total of 386 participants (222 females, mean age = 45.98 years, SD = 17.70) were enrolled, from whom sociodemographic (sex, age, years of formal education) and anthropometric (BMI and WC) data were collected. Executive functions were evaluated using the Frontal Assessment Battery–15 (FAB15). The results showed the increased effectiveness of WC over BMI in examining the relationships between executive functions, sex differences, and body weight. In particular, this study revealed that there was a significant moderating effect of sex at comparable levels of executive functioning. Specifically, women with higher executive performance had lower WCs than their male counterparts, suggesting that executive function has a greater impact on WC in women than in men. Our findings highlight the importance of conducting more in-depth investigations of the complex relationship between cognitive deficits and weight gain, considering confounding variables of behavioral, psychobiological, and neurophysiological origin.

https://doi.org/10.3390/bs14030258

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https://doi.org/10.1016/j.jcbs.2024.100853

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Surveys of the Italian population typically assess general sexual behaviors (e.g., oral, vaginal and anal intercourse). However, little is known about other sexual behavior such as rough sexual behaviors, choking and slapping. Thus, an online cross-sectional survey of 4618 Italian participants was conducted. In the past month, the most prevalent sexual behaviors were solo masturbation (93.6%), partner masturbation (80.0%), oral sex (71.4% received, 75.9% performed), penile–vaginal intercourse (75.7%) and anal intercourse (12.5% received, 7.1% performed). Regarding rough sexual behaviors, the most common behaviors performed were spanking (23.3% received, 55.5% performed), choking (13.2% receive, 60.0% performed), slapping (30.1% received, 20.9% performed) and name calling (44.5% received, 37.0% performed). Our results suggest a gender difference where men and transgender/non-binary individuals perform more rough sexual behaviors compared to women. Moreover, regarding the role of consent in behaviors such as choking and slapping, our results highlight the importance of sexual and affective education to implement sexual assertiveness. In conclusion, this study adds knowledge to the limited literature on this topic, especially with respect to the Italian population.

https://doi.org/10.3390/sexes5020005

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Background: Recent literature highlighted the relevance of parenting strategies and emotions in dealing with children with ADHD and showed that these dimensions were highly affected by the COVID-19 lockdowns. Thus, our research investigated the impact that the COVID-19 pandemic had on caregivers of children with attention deficit hyperactivity disorder (ADHD). We focused on the role of medications, children’s age, and distance learning on changes in caregivers’ emotions and parenting strategies.

Methods: Nine hundred ninety-two caregivers completed an anonymous online questionnaire. The survey enquired caregivers about children’s pharmacological therapy, difficulties in distance learning, and caregivers’ parenting strategies and emotions before and during the lockdown.

Results: Our results showed that caregivers experienced relevant difficulties in distance learning and that they felt more frustration emotions and employed more negative parenting strategies than before the pandemic. While pharmacological therapy was not a significant predictor of changes in neither positive nor negative parenting strategies, children’s age and learning burden proved to predict caregivers’ changes in positive parenting strategies. Moreover, our mediation analysis showed that the learning burden (e.g., homework increasing and children’s reliance on caregivers) partially mediates the effect of age on changes in positive strategies. The older the children, the less the burden, and the less the change in positive strategies.

Conclusions: These results describe lockdown’s impact on caregivers’ experience in dealing with children with ADHD and explain how they adapted to it by changing their parenting strategies.

DOI: 10.23736/S2724-5276.24.07379-8

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Introduction: Parents vary in their gradual adaptation to the demands of caring for an autistic child. Their experiences can be positive, negative, or a combination of both, depending on the severity of the cases and various personal and social factors. Cross-cultural comparisons can aid in understanding how contextual factors, such as the availability of social and health services, and cultural factors, such as family relationships and the distribution of care burden, may influence the caregiving experience. However, there is a limited amount of cross-cultural research on this topic, which is almost exclusively quantitative.

Aims and methods: From an ecocultural perspective, our interview-based study aimed to explore the experiences of Australian (15) and Italian (11) parents of autistic children living in their respective countries.

Results: The analysis identified three main themes. Life through autism, autism through life: coexisting with an unexpected life partner, Parenting autistic children: reorganization of parents’ subjectivity and familiar dynamics, and The unseen side of disability: autism communities between inclusion and segregation.

Discussion: Our comparative approach reveals both commonalities and differences between the two groups of participants. The similarities support features previously identified in the literature: the emotional and physical burden on parents and the positive impact on parental identity. The differences relate to the diagnostic process, interactions with health professionals, the impact of autism on family dynamics and parental perspectives, and the role assigned to siblings. Despite facing similar challenges, these differences reveal how Italian and Australian parents articulate different understandings linked to social and cultural differences.

https://doi.org/10.3389/fpsyg.2024.1409234

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This study explored the relationships among psychological, relational, and sexual factors and their impact on sexual satisfaction among Italian women during the COVID-19 lockdown. Data were collected via an online survey with 3803 participants. The survey assessed mental health, relationship quality, frequency of sexual intercourse, frequency of masturbation, body awareness, and sexual satisfaction. Correlation analyses revealed positive relationships among all the variables and negative relationships with low mental health. A network analysis showed that sexual satisfaction was the most central variable, strongly linked to relationship quality, frequency of sexual intercourse, and body awareness. An exploratory mediation model examined the indirect effects of mental health and frequency of masturbation on sexual satisfaction through the other variables as mediators. The results indicated that mental health negatively influenced sexual satisfaction both directly and indirectly through relationship quality and body awareness, while frequency of masturbation had a positive indirect effect through body awareness. These findings highlight the complex interplay among mental health, body awareness, relational factors, and sexual satisfaction, emphasizing the importance of holistic approaches in enhancing sexual well-being. Future research should focus on longitudinal studies to establish causality and explore interventions that promote positive body awareness and relationship quality.

https://doi.org/10.3390/sexes5040031

Objectives: Approximately one-third of bariatric surgery patients experience weight regain or suboptimal weight loss within five years post-surgery. Pathological eating styles and psychopathological traits (e.g., emotion dysregulation) are recognized as potential hindrances to sustain weight loss efforts and are implicated in obesity development. A comprehensive understanding of these variables and their interplays is still lacking, despite their potential significance in developing more effective clinical interventions for bariatric patients. We investigate the prevalence of and interactions between pathological eating styles and psychopathological traits in this population.

Materials and methods: 110 bariatric surgery candidates were characterized using the Binge Eating Scale (BES), Hamilton Depression/Anxiety Scales (HAM-D/A), Barratt Impulsiveness Scale (BIS-11), Experiences in Close Relationships (ECR), Difficulties in Emotion Regulation Scale (DERS). We analyzed these variables with multiple logistic regression analyses and network analysis.

Results: Patients with pathological eating styles showed more pronounced anxiety/depressive symptoms and emotion dysregulation. Network analysis revealed strong connections between BES and DERS, with DERS also displaying robust connections with HAM-A/D and ECR scales. DERS and attention impulsivity (BIS-11-A) emerged as the strongest nodes in the network.

Discussion: Our findings demonstrate the mediating role of emotion dysregulation between pathological eating styles and psychopathological traits, supporting existing literature on the association between psychopathological traits, insecure attachment styles, and pathological eating behaviors. This research emphasizes the significance of emotion regulation in the complex network of variables contributing to obesity, and its potential impact on bariatric surgery outcomes. Interventions focusing on emotion regulation may thus lead to improved clinical outcomes for bariatric patients.

https://doi.org/10.3389/fpsyt.2024.1495351

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Objectives: Approximately one-third of bariatric surgery patients experience weight regain or suboptimal weight loss within five years post-surgery. Pathological eating styles and psychopathological traits (e.g., emotion dysregulation) are recognized as potential hindrances to sustain weight loss efforts and are implicated in obesity development. A comprehensive understanding of these variables and their interplays is still lacking, despite their potential significance in developing more effective clinical interventions for bariatric patients. We investigate the prevalence of and interactions between pathological eating styles and psychopathological traits in this population.

Materials and methods: 110 bariatric surgery candidates were characterized using the Binge Eating Scale (BES), Hamilton Depression/Anxiety Scales (HAM-D/A), Barratt Impulsiveness Scale (BIS-11), Experiences in Close Relationships (ECR), Difficulties in Emotion Regulation Scale (DERS). We analyzed these variables with multiple logistic regression analyses and network analysis.

Results: Patients with pathological eating styles showed more pronounced anxiety/depressive symptoms and emotion dysregulation. Network analysis revealed strong connections between BES and DERS, with DERS also displaying robust connections with HAM-A/D and ECR scales. DERS and attention impulsivity (BIS-11-A) emerged as the strongest nodes in the network.

Discussion: Our findings demonstrate the mediating role of emotion dysregulation between pathological eating styles and psychopathological traits, supporting existing literature on the association between psychopathological traits, insecure attachment styles, and pathological eating behaviors. This research emphasizes the significance of emotion regulation in the complex network of variables contributing to obesity, and its potential impact on bariatric surgery outcomes. Interventions focusing on emotion regulation may thus lead to improved clinical outcomes for bariatric patients.

https://doi.org/10.3389/fpsyt.2024.1369720

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Background: Stress is a significant factor influencing the mental well-being of students, and mindfulness strategies have been associated with reduced academic stress. Nevertheless, there is a limited body of research investigating stress and trait mindfulness in a sample of Italian university students. This study aims to explore the relationship between academic stress, effort-reward imbalance, and trait mindfulness. Methods: Perceived stress, effort-reward imbalance, and trait mindfulness in 442 Italian university students (mean age = 23.37 ± 4.33) were assessed through the Perceived Stress Scale (PSS), Effort-Reward Imbalance – Student Questionnaire (ERI-SQ) and Five Facet Mindfulness Questionnaire (FFMQ). Results: Pearson correlation analysis showed that PSS negatively correlates with FFMQ and it positively correlates with ERI-SQ, while FFMQ negatively correlates with ERI-SQ. Furthermore, mediation analysis revealed that FFMQ partially mediates the effect of ERI-SQ on PSS. Conclusions: This study provides the first examination of the relationships between perceived stress, effort-reward imbalance, and trait mindfulness among Italian students. The findings suggest that trait mindfulness is associated with lower levels of perceived stress and could potentially mediate the relationship between effort-reward imbalance and stress. These insights may inform future research and interventions aimed at reducing academic stress.

https://doi.org/10.1177/00332941241306657

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This study investigates dietary supplement use among rugby players and their general health, focusing on prevalence and underlying motivations. Involving 92 athletes, it examines the relationship between supplement usage, motivations, and health outcomes using the 36-item Short Form Health Survey and a 24-item ad hoc questionnaire. Findings reveal a high frequency of supplement usage, motivated by desires to enhance performance, appearance, and mood. Significant differences in health-related quality of life are found between users and non-users, particularly in mental health, social functioning, and emotional stability. Motivations like performance enhancement and body shape manipulation were linked to altered health perceptions, indicating the psychosocial impacts of supplementation. This study emphasizes the need to consider the holistic effects of supplements on athlete well-being, advocating for a balanced approach prioritizing both physical and mental health. It calls for increased awareness among athletes, coaches, and sports professionals about the potential risks and benefits of supplement use and the importance of informed decision-making. Additionally, it highlights the need for further research to understand the mechanisms of supplement use and its impact on athlete health, aiming to enhance sports science and promote overall athlete well-being in competitive environments.

https://doi.org/10.3390/sports12100270

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Excoriation (Skin Picking) Disorder (SPD) is a psychiatric condition characterized by repetitive skin picking, often affecting areas like the face, arms, and hands. It has its own diagnostic classification in ICD-10, DSM-5-TR and PDM-2. Individuals with SPD may use various tools to pick at their skin and often struggle to stop the behavior. The disorder typically arises during adolescence and is more common in females, with a lifetime prevalence of 1.4% in adults. SPD is associated with decreased quality of life and increased rates of anxiety disorders, depression, and substance abuse. Validated assessment tools are essential for diagnosing and monitoring SPD symptoms. The Skin Picking Scale (SPS), Skin Picking Scale-Revised (SPS-R), Skin Picking Impact Scale (SPIS), and Skin Picking Symptom Assessment Scale (SP-SAS) are commonly used instruments for evaluating the severity of SPD symptoms. While these tools have shown reliability and validity, there are limitations, including potential biases in self-reporting and the need for further validation in different populations and languages. Future research is needed to enhance the effectiveness of screening and assessment tools for SPD in clinical settings.

https://doi.org/10.1007/s12144-024-06300-1

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The developing domain of mental health in sports has gained much interest, acknowledging its pivotal role in athlete performance and well-being. The aim of this research is to provide a quantitative description concerning the levels of mental health, physical activity, cognitive fusion, cognitive flexibility, and coping strategies that characterize rugby athletes by using a data-driven approach. A total of 92 rugby athletes took part in this study and filled out a set of self-administered questionnaires. A correlational analysis showed that general well-being was positively associated with years spent playing rugby (r = 0.23) and coping mechanisms (r = 0.29). Athletes’ well-being was also negatively correlated with cognitive inflexibility (r = −0.41) and cognitive fusion (r = −0.39). A k-means cluster analysis identified two unique groups: group 1, characterized by higher levels of psychological well-being, lower levels of physical activity, greater cognitive flexibility, improved coping techniques, and reduced cognitive fusion, and group 2, which exhibits opposite characteristics. The discrepancies observed in psychological characteristics such as coping strategies, cognitive fusion, and cognitive inflexibility highlight their potential impact on the general health of rugby players. To comprehend the complex interplay between psychological and physical elements in rugby athletes, long-term studies with larger samples are crucial.

https://doi.org/10.3390/jpm14030292

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The adoption of Artificial Intelligence-based chatbots, including ChatGPT, in various sectors has raised concerns about their implications in higher education and scientific research. While the academic world aims to foster critical thinking and produce reliable research, the use of chatbots has elicited resistance from some academics due to fears of inaccuracies. In this paper, we extensively examine this phenomenon in higher education and scientific research, seeking to understand its practical applications, limitations, and potential risks. We investigated how ChatGPT is currently being used by academia, young researchers, and students. We also identified its areas of application and conducted trials by engaging ChatGPT, with transcripts included in the paper. Based on our findings, we discuss the results in the context of the needs in higher education and scientific research, presenting guidelines for responsible adoption. We distinguish positive use cases, areas requiring caution, explicit limitations of ChatGPT, and cases of unethical use. Importantly, we view ChatGPT as a valuable technological innovation but emphasize the necessity for thoughtful and responsible implementation. While we do not consider its use inherently deceitful, consistent, and shared guidelines are essential to ensure its ethical and effective application.

https://doi.org/10.1177/27538699241231862

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Tourette syndrome (TS) is a high-incidence neurobehavioral disorder that generally begins in childhood. Several factors play a role in its etiology, including genetic influence and auto-immune activation by streptococcal infections. In general, symptoms subside after the end of adolescence, but, in a significant number of patients, they remain in adulthood. In this study, we evaluated temporal variations in the two core clinical features of TS including tics and obsessive–compulsive disorder (OCD) symptoms. An observational longitudinal study lasting 15 months (2017–2019) was conducted on a cohort of 24 people recruited in Milan (Italy) who were diagnosed with a subtype of TS known as obsessive–compulsive tic disorder. Inclusion criteria included a global score of the Yale global tic severity scale (Y-GTSS) > 50, a Yale–Brown obsessive–compulsive scale (Y-BOCS) global score > 15, and TS onset at least one year prior. Y-GTSS and Y-BOCS data were acquired at six time points, together with local environmental data. Tics, but not OCD symptoms, were found to be more severe in spring and summer compared with winter and autumn (p < 0.001). Changes in tics displayed an appreciable oscillation pattern in the same subject and also a clear synchrony among different subjects, indicating an external orchestrating factor. Ambient temperature showed a significant correlation with Y-GTSS measurements (p < 0.001). We argue that the increase in tics observed during hot seasons can be related to increasing ambient temperature. We believe that our results can shed light on the seasonal dynamics of TS symptomatology and provide clues for preventing their worsening over the year.

https://doi.org/10.3390/biomedicines12081668

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Metacognition encompasses the capability to monitor and control one’s cognitive processes, with metamemory and metadecision configuring among the most studied higher order functions. Although imaging experiments evaluated the role of disparate brain regions, neural substrates of metacognitive judgments remain undetermined. The aim of this systematic review is to summarize and discuss the available evidence concerning the neural bases of metacognition which has been collected by assessing the effects of noninvasive brain stimulation (NIBS) on human subjects’ metacognitive capacities. Based on such literature analysis, our goal is, at first, to verify whether prospective and retrospective second-order judgments are localized within separate brain circuits and, subsequently, to provide compelling clues useful for identifying new targets for future NIBS studies. The search was conducted following the preferred reporting items for systematic reviews and meta-analyses guidelines among PubMed, PsycINFO, PsycARTICLES, PSYNDEX, MEDLINE, and ERIC databases. Overall, 25 studies met the eligibility criteria, yielding a total of 36 experiments employing transcranial magnetic stimulation and 16 ones making use of transcranial electrical stimulation techniques, including transcranial direct current stimulation and transcranial alternating current stimulation. Importantly, we found that both perspective and retrospective judgments about both memory and perceptual decision-making performances depend on the activation of the anterior and lateral portions of the prefrontal cortex, as well as on the activity of more caudal regions such as the premotor cortex and the precuneus. Combining this evidence with results from previous imaging and lesion studies, we advance ventromedial prefrontal cortex as a promising target for future NIBS studies.

https://doi.org/10.1002/jnr.25330

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The phenomenon of neural plasticity pertains to the intrinsic capacity of neurons to undergo structural and functional reconfiguration through learning and experiential interaction with the environment. These changes could manifest themselves not only as a consequence of various life experiences but also following therapeutic interventions, including the application of noninvasive brain stimulation (NIBS) and psychotherapy. As standalone therapies, both NIBS and psychotherapy have demonstrated their efficacy in the amelioration of psychiatric disorders’ symptoms, with a certain variability in terms of effect sizes and duration. Consequently, scholars suggested the convenience of integrating the two interventions into a multimodal treatment to boost and prolong the therapeutic outcomes. Such an approach is still in its infancy, and the physiological underpinnings substantiating the effectiveness and utility of combined interventions are still to be clarified. Therefore, this opinion paper aims to provide a theoretical framework consisting of compelling arguments as to why adding NIBS to psychotherapy can promote therapeutic change. Namely, we will discuss the physiological effects of the two interventions, thus providing a rationale to explain the potential advantages of a combined approach.

https://doi.org/10.1155/np/7853199

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Current pharmacological treatments for major depressive disorder (MDD) are often only partially effective, with many patients experiencing no significant benefit, leading to treatment-resistant depression (TRD). Psilocybin, a classical serotonergic psychedelic, has emerged as a notable emerging treatment for such disorders. The aim of this systematic review and meta-analysis is to summarize and discuss the most recent evidence about the therapeutic effects of single-dose and two-dose psilocybin administration on the severity of depressive symptoms, as well as compare the efficacy of these interventions among patients with a primary diagnosis of MDD or TRD. Articles were collected from EBSCOhost and PubMed following the PRISMA guidelines, yielding 425 articles with 138 duplicates. After screening 287 records, 12 studies met the eligibility criteria and were included in the review. A quantitative analysis of the studies indicates that psilocybin is highly effective in reducing depressive symptoms severity among patients with primary MDD or TRD. Both single-dose and two-dose psilocybin treatments significantly reduced depressive symptoms severity, with two-dose administration sometimes yielding more pronounced and lasting effects. However, it is unclear if this was solely due to dosage or other factors. Future research should include standardized trials comparing these dosing strategies to better inform clinical practice.

https://doi.org/10.3390/brainsci14080829

ABSTRACT

Major depressive disorder (MDD) is a debilitating mental illness, and it is considered to be one of the leading causes of disability globally. The etiology of MDD is multifactorial, involving an interplay between biological, psychological, and social factors. Early life represents a critical period for development. Exposure to adverse childhood experiences is a major contributor to the global burden of disease and disability, doubling the risk of developing MDD later in life. Evidence suggests that stressful events experienced during that timeframe play a major role in the emergence of MDD, leading to epigenetic modifications, which might, in turn, influence brain structure, function, and behavior. Neuroplasticity seems to be a primary pathogenetic mechanism of MDD, and, similarly to epigenetic mechanisms, it is particularly sensitive to stress in the early postnatal period. In this review, we will collect and discuss recent studies supporting the role of epigenetics and neuroplasticity in the pathogenesis of MDD, with a focus on early life stress (ELS). We believe that understanding the epigenetic mechanisms by which ELS affects neuroplasticity offers potential pathways for identifying novel therapeutic targets for MDD, ultimately aiming to improve treatment outcomes for this debilitating disorder.

https://doi.org/10.3390/bs14100882

ABSTRACT

I nostri risultati suggeriscono che la svalutazione della ricompensa sia un perdittore del craving indipendentemente dal trattamento con TMS e che, quest’ultimo, probabilmente agisca su altri processi cognitivi legati al desiderio e alla dipendenza. In conclusione, lo studio evidenzia l’efficacia del protocollo di TMS nel ridurre il craving nei pazienti con dipendenza. Ulteriori ricerche sono necessarie al fine di indagare la relazione tra la rapidità di svalutazione della ricompensa e il craving nel contesto della dipendenza.

https://doi.org/10.14605/PCC3032401

ABSTRACT

Iron is an essential element for the development and functionality of the brain, and anomalies in its distribution and concentration in brain tissue have been found to be associated with the most frequent neurodegenerative diseases. When magnetic resonance techniques allowed iron quantification in vivo, it was confirmed that the alteration of brain iron homeostasis is a common feature of many neurodegenerative diseases. However, whether iron is the main actor in the neurodegenerative process, or its alteration is a consequence of the degenerative process is still an open question. Because the different iron-related pathogenic mechanisms are specific for distinctive diseases, identifying the molecular mechanisms common to the various pathologies could represent a way to clarify this complex topic. Indeed, both iron overload and iron deficiency have profound consequences on cellular functioning, and both contribute to neuronal death processes in different manners, such as promoting oxidative damage, a loss of membrane integrity, a loss of proteostasis, and mitochondrial dysfunction. In this review, with the attempt to elucidate the consequences of iron dyshomeostasis for brain health, we summarize the main pathological molecular mechanisms that couple iron and neuronal death.

https://www.nature.com/articles/s41380-023-02399-z

ABSTRACT

Grazie ai miglioramenti delle terapie e delle cure assistenziali per i tumori dell’infanzia negli ultimi decenni, la popolazione di lungo sopravviventi è in continuo aumento. La leucemia è la neoplasia più comune in età pediatrica e rappresenta il 25-30% di tutti i casi registrati annualmente. L’elevato tasso di sopravvivenza è accompagnato tuttavia da un rischio di eventi avversi tardivi, incidendo sulla qualità della vita, su morbilità e mortalità. Gli eventi cardiologici tardivi, in particolare da antracicline e radioterapia, sono tra i più frequenti. Questi dati dimostrano l’importanza del fenomeno e della reale necessità di impostare un valido programma di long-term follow-up (LT-FU) per lo screening e la diagnosi precoce dei late effects (LE). Si rafforza la necessità dell’adesione al “Passaporto del Guarito” come strategia per ottenere un follow-up il più possibile personalizzato, aggiornato secondo le conoscenze scientifiche e inserito nella base solida del contesto Europeo. Il ragazzo guarito da tumore pediatrico non è quindi certo una Chimera, ma piuttosto una splendida realtà.

https://www.fondazionevarenna.it/wp-content/uploads/2024/09/FASCICOLO-1_2024_AdolescenzE.pdf

ABSTRACT

Although collective violence represents a significant public health concern, a limited number of longitudinal studies have addressed this topic, with no systematic reviews focusing on posttraumatic stress symptom (PTSS) trajectories. The present systematic review and meta-analyses examined PTSS prevalence and trajectories after exposure to collective violence. A systematic literature search across six databases (APA PsycInfo, APA PsycArticles, PSYINDEX, MEDLINE, ERIC, and PubMed) identified 771 studies that were screened for the following eligibility criteria: exposure to collective violence, adult sample, longitudinal design, PTSS assessment using validated measures, PTSS trajectories estimated using latent growth modeling, and report sample prevalence rate for each trajectory. Ten studies met the criteria, and five meta-analyses were performed to assess the overall prevalence of each trajectory. Most included studies (63.6%) identified four trajectories, characterized as low-stable, high–stable, decreasing, and delayed–worsening. The low-stable trajectory was the modal response, with a pooled prevalence of 58.0%, 95% CI [51.0, 65.0]. The high-stable prevalence was 7.0%, 95% CI [4.0, 19.0]; the decreasing trajectory was 13%, 95% CI [9.0, 17.0]; and the delayed-worsening trajectory was 8.0%, 95% CI [5.0, 10.0]. A fifth trajectory, moderately stable, had a prevalence of 19.0%, 95% CI [9.0, 29.0]. The trajectory models robustly identified clinically relevant patterns of response to collective violence, offering a contribution to the literature and a starting point for future research. Further studies are needed, as a better comprehension of symptom trajectories after collective violence events has important clinical and public health implications.

https://doi.org/10.1002/jts.23090

ABSTRACT

Background: There is evidence that the tendency to adopt a peculiar pattern of causal inference, known as attributional style, is likely related to specific patterns of psychopathology among youth. Objective: This study aims to assess preliminary psychometric properties of the Italian Children’s Attributional Style Questionnaire-Revised (CASQ-R) and to explore the presence of any subgroups of children and early adolescents from the general population who might exhibit internally homogeneous and externally heterogeneous attributional styles through latent class analysis, delving into the potential sociodemographic, namely age and gender, and clinical differences among the identified classes of attributional styles. Method: A sample of 337 children (11.29 ± 1.76 years old, 169 females, and 168 males) was recruited and their attributional styles and depressive and anxious symptoms were analyzed. Results: Two distinct classes were defined using the CASQ-R items in a latent class analysis (LCA). In particular, high levels of depressive (Kruskal–Wallis chi-squared = 9.37, df = 1, Bonferroni-adjusted p = 0.002) and school phobia (Kruskal–Wallis chi-squared = 7.17 df = 1, Bonferroni-adjusted p = 0.037) symptoms were reported by children showing an internal, global and stable attributional style for negative events and an external, specific and unstable attributional style for positive events. Conversely, low levels of depressive and school phobia symptoms were reported by children showing the opposite attributional style. Conclusions: The identified classes shed light on distinct patterns associated with depressive and anxious symptoms, offering potential insights for targeted interventions.

https://www.mdpi.com/2036-7503/16/4/96

ABSTRACT

Tic disorders (TDs) are neurodevelopmental conditions which affect 0.3–0.9% of individuals aged < 18 years. Although tics often improve or resolve spontaneously over time, treatment is often recommended. Pharmacological approaches are widely used as primary interventions. However, their side effects encouraged the development and the interest in nonpharmacological approaches, whose efficacy in pediatric populations remains poorly understood. This systematic review aimed to evaluate the efficacy of nonpharmacological treatments for children and adolescents with TDs. A literature review was performed using PubMed, EBSCOhost, and JABA databases up to 16 May 2024. Eligible articles were randomized controlled trials, written in English and published in peer-reviewed journals, investigating the efficacy of nonpharmacological treatments in pediatric populations diagnosed with TDs. Significant evidence supported the efficacy of behavioral interventions such as the Comprehensive Behavioral Intervention for Tics (CBIT), its reduced version the Habit Reversal Therapy (HRT), and the Exposure and Relapse Prevention (ERP) in reducing tics and tic-related impairment among young people, as assessed through the Yale Global Tic Severity Scale. Behavioral interventions were generally effective in reducing tics, although some studies reported higher effects on motor tics when compared to vocal tics. High level of efficacy was observed for both face-to-face and online treatments. While future studies are needed to improve treatment effects, especially on vocal tics, as well as to have a better understanding of treatment components and modalities, taken together, the present findings support the use of nonpharmacological intervention for TDs in youth.

https://doi.org/10.3390/app14209466

ABSTRACT

The frequency with which Internalizing and Externalizing symptoms co-occur suggests that, behind both domains, there may be a common susceptibility represented by a general psychopathology factor. However, it’s still unclear whether this common susceptibility is affected by age-related variations. Internalizing (i.e., Fear and Distress) and Externalizing symptoms were evaluated in 803 twin pairs from the population-based Italian Twin Registry. Model-fitting analysis was performed separately in the 6–14 and 15–18 age groups to estimate genetic and environmental contributions to the covariance among symptoms. For the 6–14 group, a multivariate Cholesky model best fitted the data, while, for the 15–18 group, the best fit was provided by a Common Pathway model in which nearly 50% of total variance of each trait was mediated by common genetic factors. Our findings support a common susceptibility behind Internalizing and Externalizing symptoms, mainly genetic in origin, that becomes more evident at the beginning of puberty.

https://doi.org/10.1007/s10578-023-01498-w

ABSTRACT

This study aims to examine the relative contribution of anger cognitions and anger rumination in predicting externalizing and internalizing problems among 180 adolescents (aged 11–18 years) using correlational and linear regression analysis. Our findings showed that anger rumination predicted both externalizing (aggressive behaviors) and internalizing problems (anxious, depressive, and somatic symptoms). In contrast, biased anger cognitions did not appear to meaningfully predict either externalizing or internalizing symptoms, with the only exception of the hostile verbal labels and catastrophic cognitive attributions, a factor that was significantly associated with both rule-breaking behaviors (ß = .339, p < .01) and aggressive behaviors (ß = .238, p < .05). Anger rumination accounted for a higher rate of variance of psychopathology compared with anger cognitions and should be addressed in interventions for either externalizing or internalizing symptoms in adolescence.

https://doi.org/10.1891/JCP-2023-0050

ABSTRACT

The utilization of non-invasive neurostimulation techniques, such as transcranial magnetic stimulation (TMS), is increasingly prevalent in psychiatry due to their efficacy and safety. Although the precise therapeutic mechanisms remain partially unclear, repetitive TMS, particularly high-frequency stimulation, may enhance cognitive functions, contributing to therapeutic benefits. This within-subjects study examined the impact of TMS on cognitive and symptomatic outcomes in patients with obsessive–compulsive disorder (OCD), substance use disorder (SUD), and major depressive disorder (MDD). A total of 44 patients underwent cognitive tests and symptom assessments before and after an intensive four-week TMS treatment phase, followed by a four-week maintenance phase. Cognitive assessments included Raven’s matrices, verbal fluency, and digit span tests, while symptom severity was measured using the Italian version of the SCL-90-R. Decision-making performance was also evaluated by administering a delay discounting (DD) test. Principal component analysis was used to generate a dimensional characterization of subjects along cognitive and symptom-related axes before and after treatment. The results indicated that TMS significantly improved symptom scores, but no significant cognitive enhancement was observed. Statistical analysis based on linear mixed-effects models confirmed these findings, showing a significant fixed effect of TMS treatment on symptoms but not on cognitive performance. DD metrics remained unchanged. These findings suggest that while TMS effectively alleviates clinical symptoms, it does not produce consistent or appreciable enhancement of cognitive functions in these protocols. This study highlights the need for more personalized and combined therapeutic approaches to maximize the benefits of TMS, potentially incorporating cognitive enhancement strategies. Future studies will be useful to explore whether the results we obtained are valid for other pathologies, cognitive tests, and stimulation protocols.

https://doi.org/10.3390/app14146178

ABSTRACT

Deficits in theory of mind (ToM), known as the ability to understand the other’s mind, have been associated with several psychopathological outcomes. The present systematic review aims to summarize the results of genetic studies that investigated gene polymorphisms associated with mentalization performance tasks in children and adults. The systematic review was carried out following PRISMA guidelines, and the literature search was conducted in PubMed and EBSCOhost using the following keywords: ‘theory of mind, mentalizing, mindreading’ and ‘gene, genetic basis’. Nineteen studies met the eligibility criteria for inclusion. Most of the literature focused on the role of DRD4, DAT1, OXTR, OXT, COMT, ZNF804A, AVP, AVPR, SCL6A4, EFHC2, MAO-A, and the family of GTF2I genes in influencing ToM. However, controversial results emerged in sustaining the link between specific genetic polymorphisms and mentalization abilities in children and adults. Available data show heterogeneous outcomes, with studies reporting an association between the same family genes in subjects of the same age and other studies reporting no correlation. This does not allow us to draw any solid conclusions but paves the way for exploring genes involved in ToM tasks.

https://doi.org/10.3390/genes15060717

ABSTRACT

Studies investigating the effects of an increasing use of social media during the pandemic on youths’ wellbeing mainly focused on screen time or Internet addiction, with mixed results. The present study aimed at investigating adolescents’ social networks use, addressing the relationship between specific motivations and psychological outcomes, also considering exposure to adversities. 1195 Italian adolescents (14–18 years) were administered the Strengths and Difficulties Questionnaire and the Internet Motives Questionnaire for Adolescents. Demographic information, exposure to adverse childhood experiences (ACEs) and Covid-19-stressors, and social network use were also investigated. High levels of psychological difficulties were detected, with 49.2% of adolescents reporting abnormal emotional symptoms. Coping was the motivation to use social media that more strongly correlated with psychological problems. The hierarchical multiple linear regression model explained 28% of SDQ emotional symptoms: adverse childhood experiences and coping motivation represented the strongest predictors. According to the moderation model, high levels of ACEs score reduced the differential effect of coping motivation on emotional symptoms. In the pandemic context, using social media to handle difficult emotions represented a relevant risk factor for adolescents’ psychological health, especially for those with lower previous adverse events. Future research should further investigate these findings and their clinical implications.

https://doi.org/10.1007/s12144-023-05008-y

ABSTRACT

Case conceptualization is a widely used tool to describe and organize patient information and plan interventions in psychotherapy. Life themes and semi-adaptive plans: Implications of biased beliefs, elicitation, and treatment (LIBET) is a new method for case conceptualization that validates the diathesis-stress model and incorporates elements from the most important theories in the CBT field. LIBET also includes process-based components as maintaining factors of psychological distress, and it is not anchored to a specific kind of psychotherapeutic approach. The LIBET-Questionnaire (LIBET-Q) is a structured interview which helps clinicians achieve a LIBET case conceptualization, co-constructed with patients. The aim of the present study was to validate the process-based section of the LIBET-Q by analyzing its factorial structure, internal consistency, convergent validity, and clinical relevance. A sample of 396 outpatients was recruited to validate the LIBET-Q, which was administered along with interviews and self-report questionnaires to investigate the presence of diagnoses, anxiety, and depression levels and global functioning and wellbeing. Results from both exploratory and confirmatory factor analyses showed a four-factor structure, with adequate consistency and good convergent validity. Process-based elements investigated with the LIBET-Q resulted in identifying different clinical populations. With satisfactory psychometric properties, the LIBET-Q turned out to be a suitable support for case conceptualization and treatment formulation. The independence of the LIBET method from a specific intervention can improve its sharing between clinicians by offering a common frame in which the rationale of every specific technique can be explained.

https://doi.org/10.1007/s10942-024-00542-5

ABSTRACT

First-line treatments for post-traumatic stress disorder (PTSD) encompass a wide range of pharmacotherapies and psychotherapies. However, many patients fail to respond to such interventions, highlighting the need for novel approaches. Due to its ability to modulate cortical activity, non-invasive brain stimulation (NIBS) could represent a valuable therapeutic tool. Therefore, the aim of this systematic review is to summarize and discuss the existing evidence on the ameliorative effects of NIBS on PTSD and comorbid anxiety and depressive symptoms. Our goal is also to debate the effectiveness of an integrated approach characterized by the combination of NIBS and psychotherapy. This search was conducted following the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines in the PubMed, PsycINFO, PsycARTICLES, PSYINDEX, MEDLINE, and ERIC databases. Overall, 31 studies met the eligibility criteria, yielding a total of 26 clinical trials employing transcranial magnetic stimulation (TMS) and 5 making use of transcranial direct-current stimulation (tDCS). From these studies, it emerged that NIBS consistently reduced overall PTSD symptoms’ severity as well as comorbid anxiety and depressive symptoms. Moreover, we speculate that combining NIBS with prolonged exposure or cognitive processing therapy might represent a promising therapeutic approach for consistently ameliorating subjects’ clinical conditions.

https://doi.org/10.3390/brainsci14030210

ABSTRACT

This study assessed the psychometric properties of the Italian version of the Preschool Anxiety Scale-Revised (PAS-R), a parent-reported measure of their preschool child’s anxiety symptoms. The participants were mothers of 279 Italian preschoolers (age 2–7 years, M = 4.5 years). According to information criteria derived from a confirmatory factor analysis, the four originally identified factors (generalized anxiety, social anxiety, separation anxiety, specific fears) provided the best fit to the data. Reliability was excellent for the total score and acceptable for the subscales. PAS-R total score showed moderate correlation with internalizing subscales of the Strengths and Difficulties Questionnaire (SDQ) and of the Child Behavior Checklist and weak correlation with the externalizing subscale of the SDQ, demonstrating convergent and concurrent validity, respectively. Test–retest reliability of the PAS-R was good after 1 month. The results suggest good psychometric properties of the Italian PAS-R, although its factor structure needs further investigation with different samples.

https://doi.org/10.1080/17405629.2023.2250120

ABSTRACT

Twin studies are cutting-edge design methodologies proper to behavioral genetics that aim to investigate how the interplay between genetic and environmental factors can concur to explain individual differences in psychopathology, temperamental traits, and behavior. This particular research design has been widely applied to the study of comorbidity between internalizing (INT) and externalizing (EXT) symptoms, especially in childhood and adolescence. Notably, the high co-occurrence of symptoms of both these diagnostic domains has led to the hypothesis that at their basis, there might be one single latent common susceptibility factor, namely p factor. Twin studies have contributed to marking a relevant turning point in this regard by highlighting the consistent genetic nature of this factor. In light of these premises, the present narrative review aims to outline the path for future twin studies in investigating the comorbidity between Cognitive Disengagement Syndrome (CDS) and INT-EXT disorders, examining the evidence supporting this need and its clinical implications. Since CDS has not been recognized as a stand-alone syndrome until very recently, research on this condition is still in its infancy and the etiological factors at the basis of its comorbidity with INT-EXT are still unclear. Being aware of the causal factors underneath the comorbidity between INT-EXT might pave the way for improving assessment diagnostic procedures as well as setting up preventive interventions for CDS.

https://dx.doi.org/10.20517/jtgg.2023.51

ABSTRACT

https://doi.org/10.1016/j.concog.2024.103731

ABSTRACT

Background

METHODS

RESULTS

Abstract

https://doi.org/10.1177/00332941241306657

ABSTRACT

L’articolo descrive il caso di una paziente di 17 anni che, a seguito di una scialoadenite, inizia a manifestare i sintomi di un acufene, ovvero la percezione di un suono avvertito in assenza di uno stimolo acustico esterno; questo sintomo è associato alla presenza di ansia e difficoltà relazionali. È stato progettato un trattamento secondo il modello dell’Acceptance and Commitment Therapy (ACT) con l’obiettivo di favorire l’adattamento attraverso l’incremento della flessibilità psicologica. Inoltre, tramite un training dell’assertività, sono state affrontate le difficoltà comunicative e relazionali. L’esito della terapia è caratterizzato dalla remissione dell’acufene e una significativa diminuzione della sintomatologia ansiosa, accompagnata da un miglioramento della sfera relazionale. In questo caso i risultati sostengono l’ACT come un trattamento utile per affrontare i problemi psicologici secondari associati al tinnito.

DOI: 10.14605/PCC3022405

Abstract

Background: People with intellectual and sensory or sensory-motor disabilities tend to have problems performing multistep tasks. To alleviate their problems, technological solutions have been developed that provide task-step instructions. Instructions are generally delivered at people’s request (eg, as they touch an area of a computer or tablet screen) or automatically, at preset intervals.

Objective: This study carried out a preliminary assessment of a new tablet-based technology system that presented task-step instructions when participants with intellectual and sensory disabilities walked close to the tablet (ie, did not require participants to perform fine motor responses on the tablet screen).

Methods: The system entailed a tablet and a wireless camera and was programmed to present instructions when participants approached the tablet, that is, when the camera positioned in front of the tablet detected them. Two instructions were available for each task step. One instruction concerned the object(s) that the participants were to collect, and the other instruction concerned the “where” and “how” the object(s) collected would need to be used. For 3 of the six participants, the two instructions were presented in succession, with the second instruction presented once the required object(s) had been collected. For the other 3 participants, the two instructions were presented simultaneously. Instructions consisted of pictorial representations combined with brief verbal phrases. The impact of the system was assessed for each of the 2 groups of participants using a nonconcurrent multiple baseline design across individuals.

Results: All participants were successful in using the system. Their mean frequency of correct task steps was close to or above 11.5 for tasks including 12 steps. Their level of correct performance tended to be much lower during the baseline phase when they were to receive the task-step instructions from a regular tablet through scrolling responses.

Conclusions: The findings, which need to be interpreted with caution given the preliminary nature of the study, suggest that the new tablet-based technology system might be useful for helping people with intellectual and sensory disabilities perform multistep tasks.

JMIR Rehabil Assist Technol 2024;11:e59315

doi:10.2196/59315